Aras Part Medical International Press International Journal of Medical Parasitology and Epidemiology Sciences 2766-6492 7 Suppl 1 2026 09 18 Evaluation of Serum and Salivary Visfatin Levels in Type 2 Diabetics with Investigation of the Relationship of SNP (rs11977021) to Susceptibility of Diabetes in the Iraqi Population S70 S75 10.34172/ijmpes.6299 EN Belqis Hamed Rabie https://orcid.org/0009-0003-2089-5535 Zainab Hadi Kamil https://orcid.org/0000-0001-6893-7201 Aizhar Hamzih Hasan Journal Article 10.34172/ijmpes.6299 2026 07 31 2026 08 15 Introduction: Type 2 diabetes and its associated issues are considered a health complaint in Iraq and the world. Recently, scientific efforts have been directed towards measuring many vital parameters in saliva because of its ease of obtaining, which serves in repeatable tests. Visfatin, which is secreted from the adipose tissue, especially the central adipose, has many roles, the most important of which is simulating the action of insulin in the type 2 diabetic patients. Methods: 54 cases of type 2 diabetic (T2DM) group and 34 non-diabetic (ND) healthy group participated in this study for the period from December 2021 to February 2022 in Baghdad - Iraq. Serum and salivary Visfatin concentrations of both groups were estimated by using an Enzyme linked Immuno-sorbent- ELISA kit, Single nucleotide polymorphisms -SNPs (rs11977021-Visfatin gene) were genotyped using the Restriction fragment length polymorphism- RFLP technique. Results: signified that the concentration of visfatin in serum and saliva in the T2DM group exhibited a medium positive significant correlation, but there was no relationship of single nucleotide polymorphism with the susceptibility to type 2 diabetes in Iraqis. Conclusion: saliva may serve as a substitute to serum in evaluating the concentration of visfatin, in addition visfatin can be considered as a useful indicator in the diagnosis or prediction of the manifestation of type 2 diabetes. Moreover, it is preferable to re-analyze the SNPs (rs11977021) in other Iraqi governorates and with a great number of participants to explain the functional role of this SNPs among Iraqis.